Manic Episodes in Bipolar Disorder Linked to Abnormal Brain Changes

This shows the outline of a headPeople with bipolar disorder who experience frequent manic episodes had faster cortical thinning, specifically in the prefrontal cortex than those who reported less frequent episodes of mania. Researchers also noted faster enlargement of the brain’s ventricles and slower thinking of the parahippocampal and fusiform cortical regions in those who experienced more frequent mania.