Higher body fat leads to increased atrophy of the brain’s gray matter and a greater risk of cognitive decline, researchers report.
A new theory proposes an imbalance of blood proteins involved in the immune system and in blood clotting networks leads to inflammation that contributes to the development of psychosis.
Mouse and human studies reveal Interleukin-3 may modify immune responses in the brain that cause cell death and lead to Alzheimer’s disease.
Aromatic turmerone, a compound derived from turmeric essential oil, and its derivatives directly affect dopamine neurons to generate neuroprotective properties in tissue culture models of Parkinson’s disease.
A diet rich in foods containing isoflavone, a plant-based compound found in legumes, chickpeas, and peanuts, that resembles estrogen, protects against multiple sclerosis symptoms in mouse models.
A diet rich in fermented foods, such as yogurt and kimchi, can help to improve gut microbiome diversity and reduce symptoms of chronic inflammation, a new study reports.
Synthetically optimizing a peptide commonly found in sunflower seeds could help provide relief for gastrointestinal pain and inflammation, a new study reports.
A new study reveals humans and mice have significant differences in how oxidative stress and inflammation trigger immune response genes in astrocytes. Researchers suggest lab models of neurodegeneration should incorporate specially engineered mouse mod…
A Western-style diet, high in omega-6 polyunsaturated fats, increases symptoms of inflammation, neuropathy, and chronic pain. However, changing to a lower-fat diet can help reverse or relieve symptoms of inflammatory pain disorders.
More frequent hospital and doctor’s office visits in the years leading up to multiple sclerosis diagnosis with early MS type symptoms are usually associated with a prodromal phase of the disease, when they should be regarded as an ongoing progression o…
Researchers found an increased inflammatory signal in patients with the C90rf72 subtype of ALS. The increased inflammatory biomarkers could be found in peripheral serum tests.
Neuroinflammation may be a key player in the pathological brain changes produced as a result of chronic opioid use. Microglia is likely responsible for the majority of the changes.
COVID-19 can spark a severe immune response in the central nervous system, affecting immune cells in the vascular system and brain.
Disregarding lab animals’ circadian rhythms can hamper reproducibility, validity, and reliability of research, researchers say.
Chronic gut inflammation can trigger the clumping of alpha-synuclein in the walls of the colon, a new study reports. Researchers found chronic inflammation in the gut during early life can exacerbate the clumping of alpha-synuclein in the brains of old…
Sustained microglia activation leads to the cells becoming senescent. This leads to an accelerated accumulation of amyloid in the brain, influencing the early stages of Alzheimer’s development.
Two medications commonly used to treat inflammation and HIV infection have been repurposed in the fight against COVID-19. Researchers found combined cepharanthine/nelfinavir therapy can hasten the clearance of coronavirus infection from a person’s lung…
Secondary infections and novel inflammatory events, even ones that occur external to the brain, amplify the brain’s immune response and detrimentally impact cognition in mouse models of Alzheimer’s disease.
Immune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. These immune cells help to guard the brain and spinal cord against inflammation and infection.
Bodily inflammation following the death of a spouse can predict future depression risk in the surviving spouse, a new study reports.