Sustained microglia activation leads to the cells becoming senescent. This leads to an accelerated accumulation of amyloid in the brain, influencing the early stages of Alzheimer’s development.
Immune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. These immune cells help to guard the brain and spinal cord against inflammation and infection.
Gray matter damage associated with multiple sclerosis progression may be caused by inflammatory reactions that lead to synaptic loss.
A newly discovered microbiome-controlled anti-inflammatory subset of astrocytes helps researchers better understand inflammation of the central nervous system and its regulation.
Microglia appear to play a key role in inflammation-associated depression.
Myelomonocytic cells, a type of immune cell, can both harm and help the brain following injury.
Microglia cells continuously survey the brain to help prevent sporadic seizures.
Study finds signs of IgA antibodies in the cerebrospinal fluid of patients with multiple sclerosis during a flare-up of the disease, but not when the patients are in remission. The findings suggest gut immune cells are involved in relapse episodes of m…
By fusing a cytokine to a blood protein, researchers have developed a new therapy to help treat multiple sclerosis.
PLCG2-P522R, a genetic variant that protects against Alzheimer’s disease, enhances key functions of immune cells.
Dropping the level of the IL-33 immune molecule increased the number of synapses in the brain. In older mice, ramping up IL-33 helped push the number of new synapses toward a more youthful state.
Study investigates whether overactive immune cells that produce neutrophil extracellular traps (NETs) are responsible for more severe and lethal cases of coronavirus.