Researchers have identified a pathway involving a protein called Rab35 in glioblastoma brain cancer. The study reports restoring the activity of Rab35 could have therapeutic benefits for those with glioblastoma.
Article Correctness Is Author's Responsibility: Designer Cytokine Makes Paralyzed Mice Walk Again
Protein hyper-interleukin-6, a “designer protein” that has to be produced via genetic engineering, enabled a paralyzed mouse to walk again.
Article Correctness Is Author's Responsibility: One in Five Brain Cancers Fueled by Overactive Mitochondria
20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial.
Article Correctness Is Author's Responsibility: Noncognitive Skills, Distinct From Cognitive Abilities, Are Important to Success Across the Life
The genetics of neurocognitive skills were associated with higher tolerance of risk, delayed fertility, less healthy-risk behavior, and a greater willingness to forgo immediate gratification.
Article Correctness Is Author's Responsibility: Autism Theory 25 Years in the Making
New autism theory is consistent with the current science on the genetics of the disorder but shifts the focus to the positive traits of ASD and historical events that altered the prevalence of autism in society.
Article Correctness Is Author's Responsibility: Effects of Huntington’s Disease Mutation May Begin in Childhood
A new study adds to the growing body of evidence that the origin of Huntington’s disease is rooted in childhood. Researchers say the HTT gene mutation affects both brain and body growth during development, and the increased susceptibility of brain cell…
Article Correctness Is Author's Responsibility: Researchers Identify and Characterize 3 Molecular Subtypes of Alzheimer’s
Using data from RNA sequencing, researchers have identified three molecular subtypes of Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Artificial Enzyme May Be First Step Toward Treatment for Parkinson’s Disease
Researchers have created an artificial enzyme that stops alpha-synuclein from spreading. The findings could have positive implications for the treatment of Parkinson’s disease.
Article Correctness Is Author's Responsibility: New Clues Why Gold Standard Treatment for Bipolar Disorder Doesn’t Work for Majority of Patients
Decreased activation of the LEF1 gene is more common in bipolar patients who do not respond to lithium.
Article Correctness Is Author's Responsibility: Clinical Criteria for Diagnosing Autism Inadequate for People With Genetic Conditions
People with one of four genetic disorders express symptoms associated with autism, although they do not meet the criteria for ASD diagnosis.
Article Correctness Is Author's Responsibility: A Faster Route to Treat Depression
Researchers used epigenetic modulators to reduce the damage done by stress to neuroplasticity. Findings reveal acute intervention in epigenetic mechanisms produced antidepressant effects more rapidly than conventional medications.
Article Correctness Is Author's Responsibility: Scientists Seek Insight Into Parkinson’s, Addiction by Tracking Gene Expression in the Brain
New studies are set to explore how gene expression alters the brain’s response to drug abuse, and to screen for genes that could help brain cells withstand Parkinson’s disease.
Article Correctness Is Author's Responsibility: “Junk DNA” Plays a Key Role in Regulating Circadian Rhythms
Researchers reveal the role hundreds of miRNAs appear to play in modulating circadian rhythm.
Article Correctness Is Author's Responsibility: Brain Cancer Linked to Tissue Healing
Study reports brain tumors may arise when damaged brain tissue does not heal correctly. Researchers say some glioblastoma form when the normal healing process gets derailed by mutations. This process could begin many years before patients become sympto…
Article Correctness Is Author's Responsibility: Tracing the Many Paths of Vision
Study supports the theory that highly specialized neurons in the brain are key to translating diverse visual stimuli into behavior.
Article Correctness Is Author's Responsibility: Nanoparticle Drug-Delivery System Developed to Treat Brain Disorders
A new nanoparticle drug-delivery system resulted in unprecedented siRNA penetration across the intact blood-brain barrier. Researchers say the system could help doctors to treat secondary injuries associated with TBI that can result in Alzheimer’s and …
Article Correctness Is Author's Responsibility: Mutations Associated With Early Onset Dementia Discovered
Disruptions in circulating white blood cells may be a key driver in ALSP, a rare form of early-onset dementia.
Article Correctness Is Author's Responsibility: Common Brain Malformation Traced to Its Genetic Roots
Chiari 1 malformation, a common brain disorder, appears to be caused to two genetic mutations associated with brain development.
Article Correctness Is Author's Responsibility: Large Transporter Protein Linked to Schizophrenia
Mutations of the ABCA13 cholesterol transport protein are associated with schizophrenia-like behaviors in mouse models.
Article Correctness Is Author's Responsibility: Diversity and Severity of Autism Symptoms Linked to Mutation Locations
The severity of autism symptoms depends on which specific functional unit within a gene is the target of the mutation.