A new preclinical study has identified the role chaperone protein imbalance plays in initiating the accumulation of tau in the brain.
Article Correctness Is Author's Responsibility: ‘Instigator’ Gene Associated With Alzheimer’s Disease Discovered
The SERPINA5 was strongly correlated with tau tangle progression in the hippocampus and cortex.
Article Correctness Is Author's Responsibility: Betaine Supplement Treats Schizophrenia in Mice
Betaine, a dietary supplement extracted from sweet beets, reduces behavioral symptoms of schizophrenia in mice with genetic risk factors for the disorder. The supplement may help protect proteins that build the cellular skeletons of neurons.
Article Correctness Is Author's Responsibility: Gene That Could Help Prevent or Delay Onset of Alzheimer’s Disease Identified
Boosting the expression of the ABCC1 gene may not only reduce amyloid plaques in the brain, it might also delay the onset of Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Neural Plasticity Depends On This Long Noncoding RNA’s Journey From Nucleus to Synapse
Study sheds new light on the role noncoded RNAs play at the synapse.
Article Correctness Is Author's Responsibility: Some Alzheimer’s Plaques May Be Protective, Not Destructive
Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, …
Article Correctness Is Author's Responsibility: Autism Develops Differently in Girls Than Boys
Study reveals there are differences in genes and the genetic burdens that underpin ASD between males and females. Researchers also found specific differences in the ways the brains of girls on the autism spectrum respond to different social cues.
Article Correctness Is Author's Responsibility: Coronavirus Does Not Infect the Brain but Still Inflicts Damage
COVID-19 may not directly infect the brain, but the virus is still capable of causing significant neurological damage, a new study reports. Researchers say the neurological changes seen as a result of coronavirus infection are likely related to inflamm…
Article Correctness Is Author's Responsibility: Study Maps Brain Regions Responsible For Intoxicating Effects of Alcohol
The effects of intoxication, such as slurred speech and poor coordination, are a result of the breakdown of alcohol products in the brain and not the liver.
Article Correctness Is Author's Responsibility: Genetic Predisposition to Schizophrenia May Increase Risk of Psychosis From Cannabis Use
While cannabis users reported more psychotic experiences than non-users generally, the effect was more pronounced in those with a genetic risk factor for schizophrenia.
Article Correctness Is Author's Responsibility: Exposure to Smells In Early Infancy Can Modulate Adult Behavior
Olfactory imprinting in infant mice has a direct impact on their social behaviors as adults.
Article Correctness Is Author's Responsibility: Spit Samples Uncover Genetic Risk Factors for Pediatric Obsessive-Compulsive Disorder
Children and young adults with a specific variant of the PTPRD gene are at greater risk of developing obsessive-compulsive disorder.
Article Correctness Is Author's Responsibility: Imbalance in Gum Bacteria Linked to Alzheimer’s Disease Biomarker
An increase in bad gum bacteria and a decrease in good bacteria is associated with amyloid-beta in cerebral spinal fluid samples of older adults. The findings add to the growing body of evidence linking periodontal disease to the development of Alzheim…
Article Correctness Is Author's Responsibility: A Discovery That “Literally Changes the Textbook”
Study of gar fish reveals the modern eye-brain connection may have evolved much earlier than previously believed.
Article Correctness Is Author's Responsibility: Aluminum Is Intricately Associated With the Neuropathology of Familial Alzheimer’s Disease
Study reveals aluminum is co-located with the tau protein in people with familial Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Higher Rates of Chronic Pain in Women Linked to Genetics
Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.
Article Correctness Is Author's Responsibility: Autism Gene Study Finds Widespread Impact to Brain’s Growth Signaling Network
Mutations in the autism-related Dyrk1a gene lead to brain undergrowth in mice. Researchers say an existing drug appears to reverse the damage.
Article Correctness Is Author's Responsibility: A Blood Test For Depression and Bipolar Disorder
A new blood test can distinguish the severity of a person’s depression and their risk for developing severe depression at a later point. The test can also determine if a person is at risk for developing bipolar disorder. Researchers say the blood test …
Article Correctness Is Author's Responsibility: Reversing a Genetic Cause of Poor Stress Responses in Mice
Study reveals the role the mouse gene Ophn1 plays in helpless behaviors and identified three methods in which to reverse the effect.
Article Correctness Is Author's Responsibility: Key Brain Molecule May Play Role in Many Brain Disorders
miRNA29 is a key cellular switch in controlling late-stage brain development. Deleting miRNA29 in mice resulted in problems associated with a range of neurodevelopmental problems, including autism and epilepsy.
