Study reveals how gene control mechanisms determine the identity of neurons in the embryonic brainstem. A failure in differentiation in developing brainstem neurons can lead to behavioral abnormalities, including ADHD.
Article Correctness Is Author's Responsibility: Cancer Cells Mediate Immune Suppression in the Brain
Myeloid cells can suppress the immune response, allowing breast cancer cells to metastasize in the brain and form secondary tumor sites.
Article Correctness Is Author's Responsibility: How a Common Mutation Leads to ‘Night Owl’ Sleep Disorder
A mutation in a gene associated with circadian rhythm extends the clock period, causing people to stay up late at night and sleep late in the mornings.
Article Correctness Is Author's Responsibility: Cause of Alzheimer’s Disease Traced to Mutation in Common Enzyme
Mutations to the MARK4 gene causes the properties of tau to change, making them more likely to aggregate and become more insoluble.
Article Correctness Is Author's Responsibility: Time-Keeping Brain Protein Influences Memory
Pigment-dispersing factor, a signalling protein that helps the brain keep track of time, also helps to regulate memory formation.
Article Correctness Is Author's Responsibility: Happiness and the Evolution of Brain Size
Study reveals a new role for serotonin in the development of the human neocortex. Serotonin acts cell-extrinsically as a growth factor for basal progenitors in the developing neocortex. Researchers report placenta-driven serotonin likely contributed to…
Article Correctness Is Author's Responsibility: How Herpes Infection May Impair Human Fetal Brain Development
Herpes virus simplex type 1 infection can spread to the fetal brain during pregnancy, resulting in an increased risk of neurodevelopmental disabilities and neurological deficits.
Article Correctness Is Author's Responsibility: How Genetic Variation Gives Rise to Differences in Mathematical Ability
Genetic variants of ROBO1 in young children are associated with gray matter volume in the right parietal cortex. This, in turn, predicts mathematical tests scored by second grade.
Article Correctness Is Author's Responsibility: Cord Blood DNA Can Hold Clues for Early Autism Diagnosis and Intervention
A distinct DNA methylation signature has been discovered in cord blood of children who are later diagnosed with autism. The findings could provide a new biomarker for early detection and intervention for ASD.
Article Correctness Is Author's Responsibility: Gene That Helps Us Know When It’s Time to Urinate Discovered
Study implicates the PIEZO2 gene in experiencing the urge to urinate. The gene helps at least two cell types in the brain to identify when the bladder is full and needs emptying.
Article Correctness Is Author's Responsibility: Study Explains the Process That Exacerbates Multiple Sclerosis
Recovery from multiple sclerosis-like symptoms in mice depends upon the ability for microglia to break down the remains of damaged cells.
Article Correctness Is Author's Responsibility: Early Trauma Influences Metabolism Across Generations
Early childhood trauma has an impact on glucose metabolism and blood composition, which are passed on to the next generation.
Article Correctness Is Author's Responsibility: STAT3 Identified as Important Factor in Emotional Reactivity
STAT3 plays a crucial role in the serotonergic system as a molecular mediator for controlling emotional reactivity. The findings establish a link between the immune system, serotonergic transmission, and affective disorders such as depression.
Article Correctness Is Author's Responsibility: Links Between Inflammation and Parkinson’s Disease Highlighted
Parkinson’s patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson’s disease and inflammation.
Article Correctness Is Author's Responsibility: Experimental Glioblastoma Therapy Shows Curative Powers
MP-Pt(IV), a second generation prodrug appears to have curative properties against glioblastoma when coupled with chemotherapy in mouse models.
Article Correctness Is Author's Responsibility: The Choroid Plexus: A Conduit for Prenatal Inflammation?
Mouse study reveals the choroid plexus can act as a conduit for inflammation that can arise from maternal inflammation, impacting fetal brain development.
Article Correctness Is Author's Responsibility: Inhibiting Epileptic Activity in the Brain
Boosting levels of the DUSP4 protein could be a novel way of preventing and treating epilepsy.
Article Correctness Is Author's Responsibility: Women’s Expected Longevity Linked to Age at Birth of Last Child
Women who give birth to their last child later in life may have an edge when it comes to longevity. Those who gave birth later in life had longer telomeres, which are biomarkers for long-term health and longevity.
Article Correctness Is Author's Responsibility: Alzheimer’s Risk Gene Disrupts Endocytosis, but Another Disease-Linked Gene Could Help
The Alzheimer’s risk gene ApoE4 hampers the process of endocytosis in astrocytes.
Article Correctness Is Author's Responsibility: Process for Regenerating Neurons in the Eye and Brain Identified
Researchers have identified a network of genes in Zebrafish that regulate the process of determining whether certain neurons will regenerate.
